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FRONTLINE TRI-ACT™
- is a spot-on insecticidal and acaricide solution, specific for dogs
- contains two active ingredients, Fipronil and Permethrin
- protects the dog from fleas and ticks, repels sandflies, mosquitoes and horseflies, eliminates sandflies and horseflies
Permethrin belongs to the type 1 class of pyrethroids. It is an insecticidal and acaricide active ingredient with repellent activity. Pyrethroids are so-called “open channel blockers” that affect the sodium channel, slowing down both its activation and inactivation properties, thus leading to hyperexcitability and death of the parasite.
Fipronil is an insecticide and acaricide belonging to the phenylpyrazole family. Fipronil and its metabolite Fipronil sulfone act on chloride channels, in particular those regulated by glutamate (Glu, chloride channels present only in invertebrates). This leads to uncontrolled activity of the central nervous system and the death of the arthropods. Fipronil kills fleas within 24 hours and ticks within 48 hours of exposure.
Fipronil and Permethrin , active ingredients of FRONTLINE TRI-ACT™ , act topically through contact with external parasites.
Usage warnings
Specific for dogs. Do not use in cats.
In cats the product can cause potentially fatal convulsions, due to the presence of permethrin. In case of accidental skin exposure, wash the cat with shampoo or soap and promptly seek veterinary care. To prevent cats from being accidentally exposed to the product, separate treated dogs from cats until the application site is dry. It is important to ensure that cats do not lick the application site of a dog that has been treated with this product. If exposure of this type occurs, seek veterinary care immediately.
In cats the product can cause potentially fatal convulsions, due to the presence of permethrin. In case of accidental skin exposure, wash the cat with shampoo or soap and promptly seek veterinary care. To prevent cats from being accidentally exposed to the product, separate treated dogs from cats until the application site is dry. It is important to ensure that cats do not lick the application site of a dog that has been treated with this product. If exposure of this type occurs, seek veterinary care immediately.
Do not use in rabbits , as potentially fatal adverse reactions may occur
Pregnancy and breastfeeding
No studies have been performed on pregnant or lactating animals with this product.
No studies have been performed on pregnant or lactating animals with this product.
Puppies
The product can be used in puppies from 8 weeks of age or weighing more than 2 kg body weight. The use of the product in dogs less than 8 weeks of age or in dogs weighing less than 2 kg is not recommended.
The product can be used in puppies from 8 weeks of age or weighing more than 2 kg body weight. The use of the product in dogs less than 8 weeks of age or in dogs weighing less than 2 kg is not recommended.
